SIGH35 vs EEOT: Fluid Responsiveness in ICU Patients

A prospective study to assess the reliability of two haemodynamic tests, SIGH35 and end-expiratory occlusion test (EEOT), to predict fluid responsiveness in critically ill patients on PSV

TESTS Trial

TESTS trial: thymosin α1's impact on 28-day mortality in sepsis

PanEcho Trial

Discover how PanEcho, an AI model, automates echocardiography interpretation with high accuracy, enhancing clinical workflows and patient care.

GASTROSAM

Safety and efficacy of high-volume intravenous rehydration for severe malnutrition and gastroenteritis in children.

Biomarkers in ICU acquired weakness

Predictive biomarkers in ICU acquired weakness.

RESCUE-3

Did transvenous diaphragm stimulation aid weaning from ventilation?

TARGET Protein Trial

Does protein augmentation affect outcome amongst ICU patients?

UK-ROX

Does target SpO2 88-92% Vs SpO2 ≥96% reduce mortality in ventilated patients?

MINT Trial

Was a liberal or restrictive transfusion strategy the way forward in MI and Anaemia?

Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients

SFY - Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients What was it? A multicenter, open-label, randomized clinical trial comparing dexmedetomidine-based and clonidine-based sedation versus propofol-based sedation (usual care) in critically ill patients on mechanical ventilation. The trial tested whether α2-adrenergic receptor agonist-based sedation reduces time to successful extubation. The Devil in... Continue Reading →

Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial

Did low dose clonidine aid sleep??

Prolonged vs shorter awake prone positioning for COVID-19 patients with acute respiratory failure: a multicenter, randomised controlled trial

SFY - Prolonged vs shorter awake prone positioning for COVID-19 patients with acute respiratory failure: a multicenter, randomised controlled trial What was it? This was a multicenter randomized trial comparing prolonged awake prone positioning (>12 hours daily for 7 days) with standard care (shorter prone positioning) in non-intubated COVID-19 patients with acute hypoxemic respiratory failure... Continue Reading →

Best #FOAMed #FOAMcc #POCUS finds – October (1)

News! Loads here...lots of your POCUS and many papers / blogs and more to check out.... Some images from the Butterfly! So here is an open and honest thread on the device with hands-on experience.   We ran a JC! Click here to see all. And the Twitter moment... Success! A great reminder to us all... Continue Reading →

Best #FOAMed #FOAMcc #POCUS finds – August (1)

News! ARDS best practice guidelines came out! The important thing is to check out the grades of evidence behind each recommendation. There is no real re-invention of the wheel, and most of the suggestions are things we are all doing already....hopefully?! Site of the month! We made website of the month with our library! A... Continue Reading →

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